Lifestyle

Personalized immunotherapy response studied in body-on-a-chip cancer models

Wake Forest researchers and clinicians are using patient-specific tumor ‘organoid’ models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people. Immunotherapies, also known as biologic therapies, activate the body’s own immune system to control, and eliminate cancer. Appendiceal cancer is […]

Lifestyle

Disrupting and restoring expression of ASD-associated gene in mice alters sociability

A team of researchers affiliated with multiple institutions in Boston has found that disrupting and restoring the expression of a gene associated with autism spectrum disorder (ASD) in mice can alter their degree of sociability. In their paper published in the journal Nature Neuroscience, the group describes experiments they conducted with sociability in mice and […]

Lifestyle

Kids’ sleep: Check in before you switch off

The struggle to get your child to go to sleep and stay asleep is something most parents can relate to. Once the bedtime battle is over and the kids have finally nodded off, many parents tune out as well. But University of South Australia researcher Professor Kurt Lushington is calling for parents to check on […]

Lifestyle

New research could keep cancer-fighting T cells from burning out before the job is done

Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion. In a new Nature Immunology study, researchers at La Jolla Institute for Immunology (LJI) report that T cells […]

Lifestyle

Researchers discover how cancer cells that spread to lymph nodes avoid immune destruction

Lymph nodes are critical to the body’s immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells. Recent experiments by investigators at Massachusetts General Hospital (MGH) and Boston University School of Medicine provide insights on the details behind this immune evasion, which […]

Lifestyle

For concussion patients, CTs offer window into recovery

CT scans for patients with concussion provide critical information about their risk for long-term impairment and potential to make a complete recovery—findings that underscore the need for physician follow-up. In a study led by UC San Francisco, researchers looked at the CT scans of 1,935 patients, ages 17 and over, whose neurological exams met criteria […]

Lifestyle

Is aging a disease? Treating it like one could be worth trillions, study says

We’re living longer, but not necessarily better. As the population over 65 in the United States is projected to double by 2060—with one in five residents in retirement age—so will the number of Americans needing long-term care services. A new study suggests targeting aging itself—rather than individual diseases associated with it—could be the secret to […]